Examination of Phytochemical Composition using GC-MS and Assessment of Antibacterial Efficacy of Indian Geranium Oil against Aeromonas Caviae

Abstract

Geranium oil, extracted from the leaves and flowers of the geranium plant, holds a significant position for its potential health benefits. This essential oil has found utility in both traditional and alternative medicinal practices, showcasing its versatility across diverse healthcare methodologies. This study systematically analyzed the chemical composition of geranium oil, identifying a diverse array of compounds. Notably, Aminoacetonitrile, 3-Nitro-2-methyl propene, and 2,6-Octadiene (E,E) emerged as predominant components in the analysis. These compounds, including acetic anhydride, serve as vital precursors in pharmaceutical drug synthesis and other organic compound formations. The antibacterial efficacy of geranium oil against Aeromonas caviae was evaluated, revealing notable inhibitory effects of 17 mm at an elevated concentration of 30 µg/µl. The mechanisms underlying this antibacterial activity may be attributed to bioactive compounds present in geranium oil, such as citronellol, geraniol, and linalool, each known for their antimicrobial properties. Further research is essential to precisely elucidate these mechanisms and comprehensively evaluate the safety and efficacy of geranium oil for potential therapeutic applications.