Steam Inhalation based Sustained Release Phytosome for the Treatment of Allergic Rhinitis

Abstract

Clinical illnesses involving respiratory tract infections are quite common and potentially dangerous. An introduction to respiratory pathophysiology and the interplay between infections and immune responses is necessary before tackling issues. The current study uses a phyto-based combination of Vitex trifolia, Ocimum sanctum, and eucalyptus oil to treat allergic rhinitis. The presence of flavonoids and phenol components may have contributed to VOE (Formulation)’s increased antioxidant activity. These results led to the conclusion that it was a superior ex vivo nasal mucosa permeability booster. Conclusion: Because there is a permeation enhancer that helps reduce respiratory complaints and relieve pain, intranasal administration of VOE (formulation) has a great potential for enhanced formulation penetration via nasal mucosa