Medicinal Plant Tax A Dorsteniacontrajerva L. and its Bioactive Compounds Isolation by Lc-Ms Analysis

Abstract

The present investigation of the bioactive compounds isolated from D. contrajervausing various solvent extractions, including acetone, benzene, ethyl acetate, hexane, and methanol. The acetone extract effectively isolated Capsaicin, D-(-)-Salicin, Sinapic acid, Diosgenin, Apigenin, and Folic acid, demonstrating the solvent’s broad utility in extracting compounds with varying polarities. The benzene extract successfully yielded Indole-3-carbinol, Artemisin, and Kaempferol-3-O-glucoside, highlighting benzene’s effectiveness in isolating non-polar and glycosylated compounds with significant therapeutic potential. Ethyl acetate was shown to be an excellent solvent for moderately polar compounds, as evidenced by the isolation of Astaxanthin, Lupeol, and Artemisinin. The hexane extract effectively isolated Hirsutine, Baicalin, and Quercetin-3-O-beta-D-galactoside, indicating its ability to selectively extract bioactive compounds with varying polarities. Finally, the methanol extract efficiently isolated Oxycodone, Gabapentin, and (-)-Epicatechin, underscoring methanol’s suitability for extracting highly polar compounds with therapeutic applications. These findings demonstrate the diverse pharmacological potential of D. contrajervaand the effectiveness of different solvents in isolating bioactive compounds with significant health benefits.